Xylazine Hydrochloride (HCl) – CAS 23076-35-9: Veterinary Sedative and Analgesic
Xylazine hydrochloride (HCl) is a potent veterinary sedative and analgesic widely used for horses, cattle, and other livestock. Acting as a centrally acting α2-adrenergic agonist, it provides sedation, muscle relaxation, and pain relief during veterinary procedures.
Important: Xylazine is not approved for human use and is strictly regulated in most countries. Legal access is limited to licensed veterinarians and approved research institutions.
This guide provides:
- Key chemical and pharmacological information
- Research and veterinary applications
- Legal procurement and safe handling guidelines
Informational: What is Xylazine Hydrochloride?
Xylazine HCl is commonly used in veterinary medicine for:
- Sedation of large animals during diagnostic or surgical procedures
- Analgesia and calming of horses, cattle, and other livestock
- Facilitating minor procedures without general anesthesia
Key Facts:
| Parameter | Details |
|---|---|
| CAS Number | 23076-35-9 |
| Molecular Formula | C12H17ClN2S |
| Purity | ≥ 99% |
| Appearance | White crystalline powder |
| Mechanism | α2-adrenergic agonist; depresses CNS signaling |
| Formulation | Sterile injectable solution |
| Dosage | Species-specific; veterinary guidance required |
Hcl/ Navigational: Legal and Safe Access
Legal access to Xylazine HCl is restricted. Safe, legal procurement options include:
- Licensed Veterinary Suppliers:
- Licensed veterinarians can order Xylazine from registered distributors
- Requires veterinary credentials and proper documentation
- Veterinary Compounding Pharmacies:
- Prepare Xylazine formulations under veterinary supervision
- Ensure dosage accuracy, quality, and regulatory compliance
- Research Institutions:
- Universities and research labs may use Xylazine HCl under strict regulatory oversight for animal studies
Tip: Always verify supplier licenses and documentation to remain compliant with local laws.
Commercial: Advantages and Disadvantages
| Feature | Advantages | Disadvantages / Risks |
|---|---|---|
| Sedation | Rapid and effective | Overdose risk if misused |
| Pain Relief | Analgesia during procedures | Not for human use |
| Cost | Less expensive than general anesthesia | Requires professional handling |
| Accessibility | Available via licensed distributors | Restricted to licensed veterinarians |
| Versatility | Can combine with other anesthetics | Recovery requires monitoring |
Key Insight: Xylazine is highly effective when used responsibly but poses serious risks if misused or obtained illegally.
Transactional: Safe Handling and Procurement
Step 1: Verify Legal Status
- Confirm regulations in your country regarding veterinary sedatives
- Ensure your practice or institution is licensed to purchase controlled drugs
Step 2: Choose a Verified Supplier
- Use GMP-certified veterinary pharmaceutical distributors
- Request a Certificate of Analysis (COA) for quality assurance
Step 3: Storage and Handling
- Store in a temperature-controlled, secure environment
- Use proper PPE to prevent accidental exposure
- Keep detailed usage and inventory records
Step 4: Administer Responsibly
- Only under veterinary supervision
- Follow species-specific dosage guidelines
- Monitor animals post-administration for adverse effects
Dosage, Effects, and Drug Interactions
- Mechanism: Inhibits norepinephrine release; reduces minimum alveolar concentration (MAC) in horses
- Effects: Sedation, analgesia, muscle relaxation, cardiovascular and respiratory depression (species-specific)
- Drug Combinations: Often used with ketamine or other anesthetics for enhanced sedation
- Caution: Misuse can lead to serious health consequences
Regulatory and Safety Considerations
- Xylazine is classified as a pharmaceutical intermediate
- Not for human use; controlled in most countries
- Appearance: White crystalline powder
- Purity: ≥ 99%
Safety Guidelines:
- Use PPE: gloves, lab coat, goggles
- Work in ventilated areas or fume hoods
- Follow veterinary dosage protocols strictly
- Dispose of waste according to institutional and legal guidelines
FAQs
Q1: Is Xylazine HCl safe for humans?
- No. It is strictly a veterinary sedative and illegal for human use.
Q2: Who can legally order Xylazine?
- Licensed veterinarians, veterinary hospitals, and approved research institutions
Q3: What precautions are necessary?
- Proper PPE, secure storage, accurate dosage, and detailed recordkeeping
Q4: Are there alternatives?
- Yes. Alternatives include detomidine, medetomidine, and general anesthetics
Conclusion
(HCl) is a highly effective veterinary sedative and analgesic when used responsibly by licensed professionals. While online curiosity exists, illegal human use is dangerous and prohibited.
Proper procurement, storage, handling, and administration ensure optimal veterinary outcomes while remaining compliant with all legal regulations.
