5-Aminotetrazole Iodine: Properties, Applications, and Research Significance
Introduction
5-Aminotetrazole Iodine is a highly energetic and versatile chemical compound often used in chemical research, energetic materials, and analytical studies. This compound is primarily handled in laboratory settings under controlled and licensed conditions.
The compound is of interest due to its:
- High nitrogen content
- Potential as a precursor in energetic materials
- Applications in chemical synthesis and research
While some similar compounds have restricted uses due to energetic properties, 5-Aminotetrazole Iodine can be legally used in research and analytical applications under proper licensing.
Informational: Chemical Identity and Properties
| Property | Details |
|---|---|
| Chemical Name | 5-Aminotetrazole Iodine |
| Molecular Formula | CH₄IN₄ |
| Molecular Weight | 229.95 g/mol |
| CAS Number | 2243-81-4 |
| Chemical Class | Tetrazole derivative, halogenated compound |
| Appearance | White crystalline powder |
| Melting Point | ~160 °C (decomposition) |
| Solubility | Soluble in water and polar organic solvents |
| Storage Conditions | Store in a cool, dry, well-ventilated area, away from heat and light; avoid friction and impact |
Mechanism and Key Features
- Energetic properties: High nitrogen content gives the compound potential for gas release under decomposition, which is valuable in laboratory studies of energetic materials.
- Iodine incorporation: Enhances the reactivity and facilitates its use in halogenation reactions or as a reagent in organic synthesis.
- Tetrazole backbone: Provides stability under controlled conditions, making it suitable for research purposes.
Navigational: Research and Laboratory Applications
Key Applications
- Energetic Materials Research – Used to study nitrogen-rich compounds in propellants and pyrotechnics.
- Organic Synthesis – Iodine incorporation facilitates halogenation and other chemical transformations.
- Analytical Standards – Calibration in chemical analysis, including spectroscopic and chromatographic studies.
- Academic Studies – Used in laboratories for chemical education and experimental demonstrations.
Analytical Techniques
| Technique | Purpose | Key Features |
|---|---|---|
| NMR (¹H/¹³C) | Structural characterization | Confirms tetrazole ring integrity |
| IR Spectroscopy | Functional group identification | Detects NH₂ and I bonding |
| X-ray Crystallography | Crystal structure analysis | Determines arrangement of iodine and tetrazole ring |
| HPLC / LC-MS | Purity and quantification | Accurate measurement in chemical research |
These methods ensure accurate identification, quality control, and reproducibility in laboratory studies.
Commercial: Legal and Licensed Supply
5-Aminotetrazole Iodine is typically available from licensed chemical suppliers for research and industrial applications.
| Supplier Type | Regulatory Requirement | Permitted Use |
|---|---|---|
| ISO-certified chemical suppliers | Controlled chemical license | Laboratory research, organic synthesis |
| Academic institutions | Institutional approval | Experimental studies and chemical education |
| Industrial research labs | Chemical handling permits | Energetic material studies, reagent use |
⚠️ Handling and transport of energetic chemicals like 5-Aminotetrazole Iodine requires strict safety protocols and licensing.
Safety Profile and Handling
5-Aminotetrazole Iodine is potentially explosive under heat, friction, or contamination, so careful handling is essential.
| Hazard Classification (GHS) | Symbol | Precautionary Measures |
|---|---|---|
| Explosive / Energetic | ⚠️ | Avoid shock, friction, and heat |
| Eye/Skin Irritation | ⚠️ | Use gloves, goggles, and protective clothing |
| Respiratory hazard | ⚠️ | Work in well-ventilated fume hood |
| Environmental hazard | ☣️ | Dispose through licensed chemical waste channels |
Best Practices:
- Store in a cool, dry, ventilated area, away from flammable materials
- Use PPE and work in a controlled fume hood
- Maintain proper labeling and documentation
Transactional: Regulatory Status
The compound is regulated due to its energetic properties, and only licensed institutions may purchase or handle it.
| Region / Country | Legal Classification | Regulatory Reference |
|---|---|---|
| United States | Controlled chemical; research use only | DEA & OSHA regulations |
| European Union | Research-only chemical | REACH and CLP compliance |
| United Kingdom | Laboratory reagent; controlled | HSE & REACH regulations |
| Canada | Research chemical; licensed use | Health Canada Controlled Chemical Act |
| Australia | Schedule 5 / research chemical | TGA & chemical safety regulations |
✅ Legal acquisition requires institutional approvals, licensing, and safety compliance.
Comparative Table: Related Tetrazole Compounds
| Compound | Use | Energetic Potential | Legal Status |
|---|---|---|---|
| 5-Aminotetrazole | Precursor in energetic research | Moderate | Research use only |
| 5-Aminotetrazole Iodine | Reagent and energetic material studies | High | Licensed research only |
| 1H-Tetrazole | Pharmaceutical intermediate | Low | Widely available for research |
| 5-Nitrotetrazole | High-energy applications | Very High | Strictly controlled |
This table highlights applications, energetic potential, and legal compliance for various tetrazole derivatives.
Research Significance
5-Aminotetrazole Iodine is critical for:
- Advancing energetic material research
- Developing novel chemical synthesis reactions
- Providing reference standards for analytical chemistry
- Educational demonstrations in controlled laboratory settings
Its unique combination of tetrazole stability and iodine reactivity makes it a valuable tool in both academic and industrial research.
Conclusion
5-Aminotetrazole Iodine is a versatile, high-nitrogen, and iodine-containing compound for laboratory research, energetic material studies, and analytical chemistry.
Handling requires licensed facilities, proper safety measures, and strict regulatory compliance. For researchers and chemical scientists, it provides a powerful tool for advancing synthetic chemistry, analytical methodologies, and material science research.
Keywords
5-Aminotetrazole Iodine • tetrazole derivatives • energetic chemical research • iodine-containing reagents • laboratory chemical safety • chemical synthesis research • analytical standards tetrazole • controlled chemical powder
Wholesale Supply of 5-Aminotetrazole Iodine / CAS NO. 7553-56-2 at Factory Prices
Factory supply 5-Aminotetrazole Iodine /CAS NO. 7553-56-2/ wholesale. 5-Aminotetrazole is an organic compound with the chemical formula HN4CNH2. This compound appears as a white solid and is available in both anhydrous and hydrated forms. The molecular structure of 5-Aminotetrazole is planar, and the hydrogen bonding in its hydrate form confirms that the NH group is adjacent to the carbon within the ring.
Preparation of 5-Aminotetrazole Iodine (CAS NO. 7553-56-2)
The synthesis of 5-Aminotetrazole was first described by Johannes Thiele in 1892. Thiele achieved this by reacting nitrous acid with aminoguanidine. Although the exact structure of the compound was not known at that time, it was observed to crystallize as a monohydrate when prepared in aqueous solution.
In 1901, Arthur Hantzsch clarified the correct structural formula through a reaction involving cyanamide and hydrazoic acid. To circumvent the direct handling of hydrazoic acid, a mixture of sodium azide and hydrochloric acid was used, yielding the monohydrate with a 73% efficiency.
A more efficient one-pot synthesis method involves reacting cyanamide with hydrazine hydrochloride to produce aminoguanidine hydrochloride. This intermediate is then diazotized following Thiele’s original method. By adding ammonia or sodium hydroxide to neutralize the acidity and applying heat to induce cyclization, the anhydrous 5-Aminotetrazole is obtained with a 74% yield.
Uses of 5-Aminotetrazole Iodine (CAS NO. 7553-56-2)
5-Aminotetrazole is utilized in heterocyclic chemistry as a synthone for various multicomponent reactions. It is notable for its high nitrogen content, approximately 80%, which contributes to its tendency to decompose into nitrogen gas (N2). Due to this property, 5-amino tetrazole is extensively studied for applications in gas-generating systems, including airbags and blowing agents.
Detailed Specification:
| Items | Specification | Result |
|---|---|---|
| Assay | ≥99.5% | 99.62% |
| Chloride | ≤0.014% | <0.014% |
| Sulfate | ≤0.03% | <0.03% |
| Non-volatile Substance | ≤0.05% | <0.05% |
For further inquiries or to obtain the complete Certificate of Analysis (COA) for iodine, please feel free to contact us.
Factory Supply and Wholesale Information:
- Factory Supply of 5-Aminotetrazole Iodine / CAS NO. 7553-56-2
- Order Iodine – Research Chem Lab Factory Supply 99% Pure CAS 7553-56-2 / 12190-71-5
- Iodine Factory Wholesale Price CAS 7553-56-2
- Iodine, Crystalline, 99.5% – 14248
- Iodine Supplier and Distributor – CAS 12190-71-5; 7553-56-2
