Buy 2,6-Dioxopiperidine-3-ammonium chloride/ CAS: 24666-56-6/ factory supply
2,6-Dioxopiperidine-3-ammonium chloride is a heterocyclic compound of interest in pharmaceutical synthesis, chemical catalysis, and organic intermediates research. It belongs to the piperidine derivative family and is often used as a precursor or reagent in the synthesis of biologically active molecules.
Structurally, the compound contains a piperidine ring substituted by two carbonyl groups (at the 2- and 6-positions) and a protonated amino group, paired with chloride as a counterion. This configuration contributes to its stability, solubility in water, and reactivity in condensation and amidation reactions.
Chemical Properties Table
| Property | Details |
|---|---|
| Chemical Name | 2,6-Dioxopiperidine-3-ammonium chloride |
| Synonyms | Succinimide-3-ammonium chloride; 3-Aminoglutaramide hydrochloride |
| Molecular Formula | C₅H₉ClN₂O₂ |
| Molecular Weight | ~164.59 g/mol |
| CAS Number | [varies depending on salt form; verify via supplier database] |
| Appearance | White to off-white crystalline solid |
| Solubility | Soluble in water and polar organic solvents |
| Melting Point | ~210–220°C (decomposes) |
| Stability | Stable under ambient conditions; hygroscopic in open air |
| Storage Conditions | Store in a cool, dry place; tightly closed container |
| Safety Classification | Non-combustible; handle with standard laboratory PPE |
Navigational: Role in Research and Industry
- Pharmaceutical Synthesis
2,6-Dioxopiperidine-3-ammonium chloride is a key intermediate in the preparation of lactam-based compounds. It can serve as a building block in developing drugs that interact with neurotransmitter pathways, enzyme inhibitors, or peptide mimetics. - Organic Reactions
- Acts as a reagent in nucleophilic substitution or ring-opening reactions.
- Useful for producing amide bonds in complex organic frameworks.
- Plays a role in designing heterocyclic scaffolds for medicinal chemistry.
- Analytical & Academic Research
- Studied for its tautomeric equilibrium between keto and enol forms.
- Used as a model compound in reaction mechanism studies.
- Found in chemical databases such as PubChem and Reaxys for reference in heterocyclic chemistry.
Commercial Insights
As an industrial chemical, 2,6-Dioxopiperidine-3-ammonium chloride is produced in small- to medium-scale batches by fine chemical manufacturers and research reagent suppliers. It’s typically offered with ≥98% purity and accompanied by a certificate of analysis (COA) for traceability.
Market Use Cases:
- R&D laboratories in pharmaceutical and materials chemistry
- Universities and institutions studying nitrogen heterocycles
- Custom synthesis companies developing intermediates for APIs (Active Pharmaceutical Ingredients)
Availability:
You can find 2,6-Dioxopiperidine-3-ammonium chloride listed by legitimate suppliers under the “research chemical” or “pharmaceutical intermediate” categories.
When sourcing, ensure that:
- The vendor is ISO-certified or REACH-registered.
- The product includes MSDS, COA, and batch traceability data.
- It complies with local import/export regulations.
Transactional: Safe and Legal Procurement
To purchase 2,6-Dioxopiperidine-3-ammonium chloride legally and responsibly:
- Identify Your Use Case
Confirm that your intended use is for laboratory, educational, or industrial synthesis purposes compliant with local laws. - Vendor Verification
Source from established chemical suppliers (e.g., Alfa Aesar, TCI Chemicals, Merck, or equivalent certified distributors).
Check for business registration, ISO 9001 certification, and safety documentation. - Documentation Requirements
Many countries require:- Purchase orders on institutional or business letterhead
- End-use declarations (especially for precursor or lab reagents)
- Compliance with environmental and workplace safety laws (OSHA, REACH, GHS)
- Shipping & Handling
Store and transport under ambient conditions in sealed containers. Avoid exposure to moisture. Dispose of residues in accordance with hazardous waste regulations.
Safety and Handling Information
| Safety Aspect | Guideline |
|---|---|
| Personal Protection | Gloves, goggles, lab coat |
| Exposure Risks | May cause mild irritation to skin, eyes, or respiratory tract |
| First Aid Measures | Rinse affected area with water; seek medical advice if persistent irritation occurs |
| Waste Disposal | Dispose of according to local environmental regulations |
| Fire Hazard | Non-flammable; may release nitrogen oxides when decomposed at high temperature |
2,6-Dioxopiperidine-3-ammonium chloride near me Conclusion
2,6-Dioxopiperidine-3-ammonium chloride plays a valuable role in heterocyclic compound synthesis and chemical research. Its versatility as an intermediate makes it significant for pharmaceutical development, organic synthesis, and academic study.
By sourcing the compound from verified suppliers, following MSDS guidelines, and maintaining regulatory compliance, researchers can use it safely and effectively for legitimate scientific work.
2,6-Dioxopiperidine-3-ammonium chloride online Keywords (for optimization)
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Supplier Information:
- Production Capacity: 20 Metric Ton/Year
- Packaging: 25 kg/drum
- Delivery Time: Immediate
- Transportation: By sea, air, or courier
- Limit Number: 100 grams
- Grade: Premium and Industrial Grade
Price: Approximately for a specified quantity, noting that HCl salt form is provided.
Chemical Properties:
- Exact Mass: 164.0352552
- Topological Polar Surface Area: 72.2 Ų
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 3
Uses:
- Research and Development: Primarily used in pharmaceutical research and development for its role in the synthesis of other compounds and in studying its effects on various biological processes.
- Intermediate: Used as an intermediate in the synthesis of lenalidomide and other compounds.
For purchasing, consider contacting suppliers who specialize in chemical and pharmaceutical intermediates, ensuring they provide quality and compliance with relevant standards. Always check the supplier’s credentials and verify the product’s specifications before making a purchase.








