2,5-Dimethoxybenzaldehyde: Properties, Applications, and Legal Industrial Supply
Introduction
2,5-Dimethoxybenzaldehyde (C9H10O3) is an aromatic aldehyde primarily used as an intermediate compound in the synthesis of pharmaceuticals, fragrances, and fine chemicals.
It’s also valuable in organic synthesis and industrial research due to its reactive aldehyde group and methoxy substitutions, which influence reactivity and solubility.
This compound has drawn attention from both chemical manufacturers and research institutions for its role in developing new aromatic compounds, essential oils, and flavoring intermediates.
This article provides a full overview of 2,5-Dimethoxybenzaldehyde, covering its properties, applications, safe handling, and legally compliant procurement pathways.
Informational: Chemical Profile and Overview
2,5-Dimethoxybenzaldehyde belongs to the methoxybenzaldehyde family, which is known for aromatic reactivity and diverse industrial utility.
It serves as a key building block in the synthesis of bioactive molecules, fragrances, and polymers.
Chemical Properties Table
| Property | Details |
|---|---|
| Chemical Name | 2,5-Dimethoxybenzaldehyde |
| Molecular Formula | C9H10O3 |
| Molecular Weight | 166.17 g/mol |
| CAS Number | 93-02-7 |
| IUPAC Name | 2,5-Dimethoxybenzaldehyde |
| Synonyms | Veratraldehyde, 2,5-DMB, DMBA |
| Chemical Class | Aromatic aldehyde |
| Appearance | Off-white to pale-yellow crystalline solid |
| Melting Point | 51–53 °C |
| Boiling Point | 274 °C (at 760 mmHg) |
| Density | 1.134 g/cm³ |
| Solubility | Soluble in ethanol, ether, and chloroform; slightly soluble in water |
| Purity | ≥99% (industrial grade) |
| Storage Conditions | Store below 25 °C, dry and well-ventilated environment |
| HS Code | 2913000090 |
This structured data ensures discoverability in scientific databases and supports regulatory documentation for laboratories and industrial users.
Navigational: Industrial and Research Applications
2,5-Dimethoxybenzaldehyde plays a significant role in several industrial and research processes due to its functional flexibility.
1. Organic Synthesis
The aldehyde group of 2,5-Dimethoxybenzaldehyde makes it ideal for condensation reactions, Grignard reactions, and reductive amination, serving as a starting point for various substituted aromatic compounds.
2. Fragrance and Flavor Industry
- Used as a precursor in producing vanillin-like and anisic scents.
- Contributes to sweet, spicy, and woody aroma notes in fragrance formulation.
- Acts as an intermediate in natural oil substitutes and synthetic perfumes.
3. Pharmaceutical and Biomedical Research
- Used in the synthesis of bioactive molecules with antioxidant and antimicrobial properties.
- Plays a role in analytical chemistry as a reference standard or reagent.
- Serves as an intermediate for potential therapeutic compounds under academic investigation.
4. Polymer and Material Science
- Employed in producing functionalized monomers and polymer precursors.
- Its electron-donating methoxy groups improve thermal stability and solubility of end products.
Commercial: Industrial Availability and Quality Standards
2,5-Dimethoxybenzaldehyde is widely available through authorized chemical suppliers catering to industrial, research, and educational sectors.
It is sold in varying purities (95–99.5%) and quantities (from grams to kilograms) to meet both laboratory-scale and production-scale requirements.
Quality Assurance Features
- High-purity analytical grade available for R&D and QC labs.
- Batch traceability with Certificate of Analysis (CoA).
- ISO 9001 and GMP-compliant manufacturing sources.
- REACH and GHS compliant labeling for export and safety.
Packaging Options
- 100g, 500g, and 1kg laboratory bottles.
- 25kg industrial drums for bulk orders.
- Airtight HDPE containers to prevent oxidation and contamination.
Transactional: Legal Supply and Safe Procurement
1. Legal Status
2,5-Dimethoxybenzaldehyde is a legally regulated industrial chemical, not a controlled substance.
However, due to its potential as an intermediate precursor in certain restricted syntheses, it is monitored under chemical safety and precursor regulations in several countries.
| Region | Regulatory Notes |
|---|---|
| United States (EPA/OSHA) | Listed under TSCA inventory; regulated for industrial handling. |
| European Union (REACH) | Compliant for import/export within EU markets. |
| China | Available for export; subject to customs declaration for aromatic intermediates. |
| India | Industrial chemical; requires standard hazard labeling. |
| Australia | Approved for research and commercial use with GHS labeling. |
2. How to Purchase Safely
To purchase 2,5-Dimethoxybenzaldehyde legally and safely:
- Verify supplier credentials (ISO, GMP, or REACH registration).
- Request documentation such as CoA, SDS, and import/export license (if applicable).
- Ensure intended use complies with industrial, academic, or analytical purposes only.
- Avoid unverified online vendors — always source from registered chemical distributors.
3. Reputable Supplier Types
- Laboratory chemical suppliers (for R&D-grade materials).
- Pharmaceutical intermediate manufacturers.
- Fine chemical exporters specializing in aromatic compounds.
Bulk buyers typically obtain quotations directly from factory distributors for custom purity levels and logistics support.
Safety and Handling Information
2,5-Dimethoxybenzaldehyde should be handled according to standard laboratory chemical safety protocols.
Hazards
- Harmful if inhaled or ingested (Category 4).
- May cause mild skin or eye irritation upon contact.
- Emits irritating fumes when heated.
Personal Protective Equipment (PPE)
- Nitrile gloves
- Safety goggles
- Lab coat
- Adequate fume hood ventilation
Storage Guidelines
- Store in a cool, dry, and well-ventilated place.
- Keep container tightly sealed.
- Avoid exposure to strong oxidizing agents and direct sunlight.
Disposal
Dispose of residues and packaging according to local hazardous waste regulations (EPA or REACH-compliant).
Environmental and Research Relevance
With increasing demand for green chemistry and bio-based materials, 2,5-dimethoxybenzaldehyde is gaining traction as a renewable aromatic intermediate derived from natural phenolic sources.
Research is ongoing into its role in:
- Eco-friendly solvent synthesis.
- Aromatic aldehyde-based pharmaceuticals.
- Advanced photopolymer and sensor materials.
This versatility ensures its continued demand in sustainable chemistry and industrial innovation.
2,5-Dimethoxybenzaldehyde near Conclusion
2,5-Dimethoxybenzaldehyde remains one of the most important aromatic aldehydes in modern industrial and laboratory chemistry.
Its chemical stability, high reactivity, and wide applicability make it indispensable for organic synthesis, fragrance manufacturing, and pharmaceutical research.
When sourced responsibly and handled under compliant conditions, it offers both scientific reliability and economic efficiency.
Its future importance in green manufacturing and regulated specialty chemistry makes it a compound of ongoing global significance.
2,5-Dimethoxybenzaldehyde online Summary
- Meta Title: 2,5-Dimethoxybenzaldehyde – Properties, Industrial Applications & Legal Supply
- Meta Description: Explore 2,5-Dimethoxybenzaldehyde (CAS 93-02-7) – chemical properties, synthesis applications, and safe legal sourcing for research and industrial use.
- Keywords: 2,5-Dimethoxybenzaldehyde, Veratraldehyde, aromatic aldehyde, organic synthesis intermediate, fragrance precursor, CAS 93-02-7, industrial chemical supplier
Uses:
- Synthesis: Used as an intermediate in the synthesis of various pharmaceuticals and organic compounds.
- Research: Employed in the study of chemical reactions and the development of new materials.
Handling and Storage:
- Storage: Store in a cool, dry place away from direct sunlight. Keep in a tightly closed container.
- Safety: Handle with care using appropriate safety gear (gloves, goggles). Ensure good ventilation in the working area.
Purchasing Information:
- Quality: Verify the supplier’s quality assurance procedures and ensure the product is tested for purity.
- Availability: Check with chemical suppliers or manufacturers for availability in bulk or smaller quantities.
Where to Buy:
- Factory Supply: For bulk purchases, contact chemical manufacturers or suppliers that offer factory direct supply.
- Online Suppliers: Reputable chemical supply companies or distributors often list this compound. Ensure they provide certifications of authenticity and quality.
Example Suppliers:
- Chemical Companies: Look for companies that specialize in fine chemicals and laboratory reagents.
- Wholesale Platforms: Platforms that handle bulk chemical sales and offer detailed product specifications and safety data.
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