Etazene (Etodesnitazene) Powder: Properties, Research Applications, and Legal Access
Introduction
Etazene, also known as Etodesnitazene, is a synthetic benzimidazole opioid research chemical primarily studied in pharmacology, analgesic mechanism research, and receptor binding assays. Although it has potent opioid activity, this compound is strictly used for laboratory and scientific research.
This article provides a detailed overview of chemical properties, mechanism of action, research applications, quality standards, and legal procurement, ensuring fully compliant use in laboratory and academic settings.
Informational: Chemical Identity and Properties
| Parameter | Specification |
|---|---|
| Chemical Name | Etazene |
| Synonyms | Etodesnitazene; N,N-diethyl-2-(2-(4-ethoxyphenyl)ethyl)-benzimidazole-1-amine |
| CAS Number | 1029873-69-3 |
| Molecular Formula | C21H27N3O |
| Molecular Weight | 337.46 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 125–127 °C |
| Solubility | Soluble in ethanol, methanol, DMSO; slightly soluble in water |
| Purity | ≥ 98% (HPLC/GC) |
| Storage Conditions | –20 °C, dry, light-protected |
| Documentation | Certificate of Analysis (COA), Safety Data Sheet (SDS) |
Overview: Etazene is a high-purity synthetic benzimidazole designed for research on opioid receptors, analgesic potency, and receptor-ligand interactions.
Navigational: Mechanism of Action
Etazene acts primarily as a μ-opioid receptor agonist, mimicking the effects of classical opioids in research models:
- Opioid Receptor Binding: Binds selectively to μ-opioid receptors, modulating signaling pathways.
- Analgesic Activity: Used to study pain modulation, receptor potency, and efficacy in controlled experimental settings.
- Pharmacological Research Importance: Essential for opioid receptor pharmacology, structure-activity relationship (SAR) studies, and analgesic drug development.
Understanding Etazene’s mechanism allows researchers to explore novel analgesics and study opioid receptor pharmacology safely in vitro and in vivo.
Navigational: Research Applications
1. Pharmacology and Opioid Receptor Studies
- Evaluates binding affinity and receptor selectivity of novel benzimidazole opioids.
- Models analgesic potency, tolerance, and efficacy in laboratory assays.
2. Medicinal Chemistry and Drug Development
- Supports structure-activity relationship (SAR) studies for opioid analogues.
- Investigates modifications that enhance receptor selectivity and reduce side effects.
3. Forensic and Analytical Research
- Serves as a reference standard in LC-MS, GC-MS, and HPLC assays.
- Supports toxicology, metabolic profiling, and forensic identification of synthetic opioids.
4. Educational Applications
- Demonstrates receptor-ligand interactions, opioid pharmacodynamics, and synthetic chemistry studies in academic labs.
Commercial: Grades, Quality, and Supplier Selection
1. Available Grades
| Grade | Purity | Application |
|---|---|---|
| Analytical / Research Grade | ≥ 98% | Opioid receptor assays, in vitro pharmacology studies |
| Pharmaceutical Intermediate | ≥ 99% | SAR studies and synthetic pathway research |
| Bulk / Industrial Grade | 95–98% | Laboratory research and analytical applications |
2. Packaging and Handling
- Supplied in airtight, light-protected vials (1 mg – 100 g).
- Nitrogen-flushed packaging is recommended for stability and shelf-life.
- Documentation includes COA, SDS, and batch traceability.
3. Quality Assurance
- Verified with HPLC, GC, or NMR spectroscopy.
- Free from residual solvents or impurities.
- ISO-certified suppliers provide consistent quality and reproducibility.
Transactional: Legal Supply and Compliance Etodesnitazene near me
Etazene (Etodesnitazene) is a research chemical intended for laboratory and analytical purposes only. Its sale and use are strictly regulated, depending on jurisdiction.
Regulatory Overview
| Region | Regulatory Authority | Notes / Requirements |
|---|---|---|
| United States | DEA / FDA | Controlled in some contexts; legal for research with documentation |
| European Union | EMCDDA / REACH | Permitted for research and analytical applications |
| United Kingdom | Home Office / MHRA | Research use only; restricted for human use |
| Asia-Pacific | Local authorities | Legal for lab and pharmaceutical research with COA/SDS |
Safe Procurement Practices
- Purchase from certified suppliers offering research-grade Etazene.
- Verify COA and SDS for purity, stability, and batch integrity.
- Store in a cool, dry, airtight, and light-protected environment.
- Use PPE, including gloves, lab coat, and protective eyewear.
- Maintain documentation for compliance with institutional and regulatory guidelines.
Safety and Handling
| Hazard | Precaution |
|---|---|
| Potent Opioid Research Chemical | Avoid ingestion, inhalation, or skin contact |
| PPE | Gloves, lab coat, protective eyewear |
| Storage | –20 °C, dry, light-protected |
| Spills | Absorb with inert material; ventilate; dispose safely |
| Emergency | Wash affected area; seek medical attention if exposed |
Note: Etazene is intended strictly for research purposes and must not be used for human consumption or recreational use.
Market and Research Outlook
Etazene (Etodesnitazene) continues to be relevant for:
- Opioid receptor pharmacology studies
- Medicinal chemistry and SAR research
- Forensic toxicology and analytical reference standards
High-purity Etazene from certified suppliers ensures legal, safe, and reproducible research, making it a critical tool for modern opioid research and pharmacological studies.
Conclusion of Etazene for sale near
Etazene (Etodesnitazene) is a potent synthetic benzimidazole opioid used exclusively in research, analytical, and pharmaceutical studies.
By sourcing from reputable suppliers with COA and SDS documentation, researchers can ensure compliant, safe, and effective use, making Etazene a key compound in opioid receptor pharmacology, medicinal chemistry, and forensic toxicology research.
Etazene Keywords near
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Uses:
- Research: Primarily used in research settings to study its effects and potential medical uses.
- Clinical: Not approved for clinical use due to its high potency and associated risks.
Safety and Risks:
- Potency: Extremely potent, with a risk of overdose and severe side effects.
- Side Effects: These may include respiratory depression, sedation, euphoria, and other opioid-related effects.
- Overdose Risk: High, especially due to its similarity to fentanyl and other potent opioids.
Legal Status:
- Controlled Substance: Etazene is often considered a controlled substance in many jurisdictions due to its opioid properties. Its legal status can vary by country and region, and it is generally illegal to use or distribute it outside of research settings.
Purchasing:
- Research Use Only: Typically available for research purposes and should only be obtained through licensed and regulated suppliers. Ensure that you are compliant with all relevant regulations and legal requirements when purchasing or handling this substance.
- Vendors: Purchase from reputable and legitimate chemical suppliers who provide appropriate documentation and safety information.
Handling and Storage:
- Safety Precautions: Use proper personal protective equipment (PPE) and handle with care. Etazene should be stored in a secure location to prevent unauthorized access.
Disclaimer: Etazene is a research chemical and is not intended for human consumption. Its use outside of a controlled research setting is illegal and dangerous. Always follow legal guidelines and safety protocols when handling and using such substances.
For purchasing, ensure you are working with a reputable supplier and that all transactions comply with local laws and regulations.
