Buy 4F-MDMB-BINACA powder/CAS 2390036-46-9/online
4F-MDMB-BINACA (also known as 4F-ADB) is a potent synthetic cannabinoid belonging to the indazole-based cannabinoid class. It has been identified in forensic toxicology investigations, seized herbal mixtures, and analytical reference materials associated with synthetic cannabinoid research.
Because this compound has been linked to severe intoxications and is controlled or restricted in many jurisdictions, information about it should be approached from a forensic, toxicological, and public-health perspective rather than recreational or consumer use.
Informational: Chemical Identity and Properties
| Parameter | Specification |
|---|---|
| Chemical Name | 4F-MDMB-BINACA |
| Synonyms | 4F-ADB; methyl 2-(1-(4-fluorobutyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate |
| CAS Number | 2743526-69-1 (commonly referenced) |
| Chemical Class | Synthetic cannabinoid |
| Molecular Formula | C19H26FN3O3 |
| Molecular Weight | 363.43 g/mol |
| Appearance | White to off-white powder |
| Solubility | Soluble in organic solvents such as methanol and acetonitrile |
| Common Laboratory Use | Forensic toxicology and analytical reference standard |
4F-MDMB-BINACA is structurally related to several highly potent synthetic cannabinoid receptor agonists (SCRAs) detected in:
- herbal smoking blends
- seized powders
- counterfeit vaping materials
- forensic toxicology samples
Navigational: Pharmacology and Mechanism of Action
Cannabinoid Receptor Activity
4F-MDMB-BINACA acts primarily as a potent agonist at:
- CB1 cannabinoid receptors
- CB2 cannabinoid receptors
Unlike naturally occurring cannabinoids such as THC, many synthetic cannabinoids display:
- significantly higher receptor affinity
- stronger potency
- less predictable toxicological profiles
Toxicological Concerns
Published toxicology literature associates potent SCRAs with:
- severe agitation
- seizures
- psychosis
- tachycardia
- respiratory depression
- unconsciousness
Because potency varies substantially between batches, forensic and public-health agencies consider compounds like 4F-MDMB-BINACA high-risk substances.
Commercial: Research and Analytical Applications
Legitimate scientific uses are generally limited to:
- analytical chemistry
- forensic toxicology
- mass spectrometry calibration
- metabolite identification studies
- receptor-binding research
Research laboratories may study:
- metabolic pathways
- receptor binding affinity
- toxicological detection methods
- Emerging Psychoactive Substance Surveillance
Analytical Detection Methods
Common laboratory techniques include:
- LC-MS/MS
- GC-MS
- UHPLC-QTOF-MS
- HPLC analytical screening
Certified reference materials are used to:
- validate forensic testing
- calibrate laboratory equipment
- confirm metabolite profiles
Transactional: Legal and Regulatory Status
4F-MDMB-BINACA is controlled or restricted in numerous jurisdictions, including:
- the United States
- the European Union
- the United Kingdom
- Australia
- several Asian countries
Regulatory agencies and drug-monitoring organizations have identified it as part of the evolving synthetic cannabinoid market.
Compliance Considerations
Authorized handling may require:
- licensed laboratory status
- controlled substance registration
- institutional approval
- documented chain-of-custody procedures
Unauthorized possession, manufacture, or distribution may violate local or international controlled-substance laws.
Safety and Handling Information
Because of the extreme potency associated with many SCRAs, laboratory handling protocols commonly include:
- nitrile gloves
- respiratory protection
- fume hood handling
- contamination prevention procedures
- secure storage and documentation
Accidental exposure may present significant toxicological risk even at very low quantities.
Forensic and Public Health Relevance
Synthetic cannabinoids such as 4F-MDMB-BINACA remain important in:
- emergency medicine surveillance
- forensic toxicology
- public-health monitoring
- customs and border enforcement
- analytical chemistry research
International agencies, including the United Nations Office on Drugs and Crime and the European Monitoring Centre for Drugs and Drug Addiction, have tracked synthetic cannabinoid trends because of their rapid emergence and associated health risks.
Conclusion
4F-MDMB-BINACA is a highly potent synthetic cannabinoid primarily relevant to:
- forensic science
- analytical toxicology
- public-health monitoring
- controlled laboratory research
Due to its toxicological risks and widespread regulatory restrictions, it should only be handled within lawful scientific and analytical contexts using appropriate safety procedures and institutional oversight.









