Buy 3-Methoxyphencyclidine (3-MeO-PCP) Online – CAS 72242-03-6
Introduction
3-Methoxyphencyclidine (3-MeO-PCP) is a dissociative arylcyclohexylamine belonging to the phencyclidine (PCP) family. Originally synthesized for neurochemical research in 1979, it has since emerged as a significant compound in forensic toxicology, analytical chemistry, and public health monitoring due to its appearance in new psychoactive substances (NPS).
As a structural analog of PCP, 3-MeO-PCP acts as an N-methyl-D-aspartate (NMDA) receptor antagonist, making it valuable for receptor binding studies and laboratory reference standards. This guide provides a detailed, research-focused overview of 3-MeO-PCP’s chemical properties, analytical identification, safety measures, and regulatory framework.
⚠️ Note: 3-MeO-PCP is strictly for research and compliance purposes. It is not approved for human consumption.
Chemical Properties and Structure
3-MeO-PCP is a methoxy-substituted analog of PCP, featuring a methoxy group (-OCH₃) at the meta-position of the phenyl ring. This structural modification influences its pharmacokinetics, receptor-binding properties, and forensic identification.
| Property | Details |
|---|---|
| Chemical Name | 3-Methoxyphencyclidine |
| Abbreviation | 3-MeO-PCP |
| CAS Number | 72242-03-6 |
| Molecular Formula | C18H27NO |
| Molecular Weight | 273.41 g/mol |
| IUPAC Name | 1-[1-(3-Methoxyphenyl)cyclohexyl]piperidine |
| Chemical Class | Arylcyclohexylamine |
| Physical Appearance | Off-white crystalline powder |
| Melting Point | 90–94 °C |
| Solubility | Soluble in ethanol, methanol, DMSO, and other organic solvents |
| Storage | 2–8 °C, protected from light and moisture |
| Purity (Research Standard) | ≥98% HPLC-verified |
| Intended Use | Analytical reference, forensic research only |
This information is essential for forensic chemists and research professionals confirming compound identity during method validation or laboratory analysis.
Analytical and Forensic Applications of Buy 3-Methoxyphencyclidine/ 3-MeO-PCP/ CAS 72242-03-6 online
3-MeO-PCP is increasingly detected in toxicological casework involving emerging dissociative substances. Laboratories utilize advanced analytical methods to differentiate it from related compounds like 3-HO-PCP and 4-MeO-PCP.
Key Analytical Techniques
| Technique | Purpose |
|---|---|
| Gas Chromatography–Mass Spectrometry (GC-MS) | Provides fragmentation patterns for NPS databases |
| Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) | Detects trace levels in blood, urine, plasma |
| Fourier-Transform Infrared Spectroscopy (FTIR) | Confirms functional group composition |
| Nuclear Magnetic Resonance (NMR) | Determines molecular structure and validates reference standards |
Applications in Forensic Toxicology:
- Differentiating 3-MeO-PCP from analogues
- Detecting novel psychoactive trends in seized samples
- Supporting court-admissible analytical evidence
Research and Laboratory Use of Buy 3-Methoxyphencyclidine/ 3-MeO-PCP/ CAS 72242-03-6 online
While 3-MeO-PCP is regulated worldwide, certified suppliers provide traceable analytical quantities for legitimate research.
Authorized Use Cases
- Forensic and toxicological method validation
- NMDA receptor pharmacology and comparative studies
- Academic research on arylcyclohexylamine metabolism and toxicodynamics
- Chemical education and NPS identification training
Best Practices for Sourcing
- Purchase from ISO/IEC 17025-accredited suppliers
- Obtain Certificates of Analysis (CoA), MSDS, and purity verification
- Ensure batch traceability and compliance documentation
Legal and Regulatory Framework
Due to its psychoactive potential, 3-MeO-PCP is controlled in most jurisdictions.
| Region | Legal Status | Reference |
|---|---|---|
| United States | Schedule I (Federal Analog Act) | DEA Controlled Substances Act |
| European Union | Controlled NPS | EMCDDA monitoring framework |
| United Kingdom | Class B | Misuse of Drugs Act 1971 / Psychoactive Substances Act 2016 |
| Canada | Schedule I | Controlled Drugs and Substances Act |
| Australia | Schedule 9 | Poisons Standard 2025 |
| Japan | Designated Substance | Ministry of Health, Labour, and Welfare |
Legal Access Requirements:
- Restricted to licensed labs, universities, or government agencies
- Secure storage with restricted access
- Full documentation of acquisition, use, and disposal
Unauthorized possession, synthesis, or distribution is illegal and carries significant penalties.
Health, Safety, and Laboratory Handling
Even in research contexts, 3-MeO-PCP must be handled as a potentially neuroactive chemical.
Safety Recommendations
- Work in fume hoods with gloves and protective clothing
- Avoid aerosolization or skin/eye contact
- Dispose of waste according to EPA and OECD hazardous protocols
- Maintain eyewash stations and safety showers in the lab
Environmental precautions are crucial, as these compounds may persist in wastewater and aquatic ecosystems.
Research Ethics and Compliance
For authorized research:
- Follow Good Laboratory Practices (GLP)
- Obtain IRB or Ethics Committee oversight for any biological studies
- Report findings transparently to national toxicology or forensic networks
Compliance ensures research supports public safety, scientific knowledge, and drug harm reduction rather than unauthorized use.
Conclusion
3-Methoxyphencyclidine (3-MeO-PCP) is a forensic reference compound with significant analytical and pharmacological relevance. Proper research under licensed laboratory conditions enhances detection methods, regulatory awareness, and public health initiatives.
Key Takeaways
- 3-MeO-PCP is strictly a research and forensic chemical, not for clinical or recreational use
- Used in toxicological and NMDA receptor studies
- Internationally controlled, legal only under authorized research
- Must follow GLP, ISO, and regulatory frameworks
- Supports global forensic and public health research on NPS
Keywords: “3-Methoxyphencyclidine forensic research,” “arylcyclohexylamine analysis,” “controlled substance reference material”
Background Information
- Synthesis Year: 1979
- Market Availability: Since 2011 as a research chemical
- Structure: Related to PCP and other dissociatives like 4-MeO-PCP
- Notable Myth: Does not exhibit opioid-like properties
Potential Research Applications
| Application | Notes |
|---|---|
| Neuroplasticity | Possible enhancement of brain adaptability and recovery |
| Anxiety & Depression | Interaction with serotonin and NMDA receptors |
| Addiction Treatment | May reduce cravings and relapse potential |
| Pain Management | Potential analgesic properties |
Buy 3-Methoxyphencyclidine/ 3-MeO-PCP/ CAS 72242-03-6 online Handling, Storage, and Purchasing
- Form: Powder
- Storage: Dry, cool place to maintain stability
- Safety: Follow laboratory protocols, PPE required
Purchasing Guidelines
- Verify third-party purity testing
- Purchase from reputable research chemical vendors
- Ensure safe international shipping with compliance measures
⚠️ Research chemical: Not approved for medical use. Verify legal status locally before purchase.
