17?-Methyltestosterone: Properties, Uses, Research Applications, and Legal Access
Introduction
17?-Methyltestosterone is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. It is widely used in clinical endocrinology, pharmaceutical formulation, and academic research for studying hormone therapy, androgen receptor function, and anabolic mechanisms.
While once prescribed for certain androgen deficiency and growth-related conditions, today it serves primarily as a research and reference compound used under strict regulatory compliance.
This guide explores its properties, mechanism, applications, safety, and legal supply, written to serve researchers, pharmaceutical manufacturers, and forensic analysts.
Informational: Chemical Identity and Properties 17?-Methyltestosterone ONLINE
| Parameter | Specification |
|---|---|
| Chemical Name | 17?-Methyltestosterone |
| Synonyms | 17?-MT, Methyltestosterone, Metandren, Android |
| CAS Number | 58-18-4 |
| Molecular Formula | C20H30O2 |
| Molecular Weight | 302.45 g/mol |
| Chemical Structure | Synthetic derivative of testosterone with a methyl group at the 17? position |
| Appearance | White to off-white crystalline powder |
| Purity | ? 98% (HPLC) |
| Melting Point | 162–167 °C |
| Solubility | Soluble in ethanol, chloroform, and acetone; insoluble in water |
| Storage | Store in a cool, dry place (2–8 °C), away from light |
| Stability | Stable under normal laboratory conditions |
| Documentation | Certificate of Analysis (COA), Material Safety Data Sheet (MSDS) available |
The methyl group at the 17? position enhances its oral bioavailability and resistance to hepatic metabolism, a key reason it has been widely studied for pharmacokinetic modeling.
Navigational: Mechanism of Action 17?-Methyltestosterone
1. Androgen Receptor Binding
17?-Methyltestosterone binds to androgen receptors (AR) in muscle, bone, and reproductive tissues, promoting protein synthesis and nitrogen retention.
2. Anabolic and Androgenic Effects
- Anabolic: Supports muscle and bone tissue growth, aiding research into muscle wasting and bone density.
- Androgenic: Regulates development of male secondary sexual characteristics.
3. Pharmacological Research Value
Researchers use 17?-Methyltestosterone to:
- Study androgen receptor selectivity and modulation.
- Investigate hormone replacement therapy models.
- Analyze hepatic metabolism and structure-activity relationships (SAR).
Informational: Laboratory and Clinical Research Applications
17?-Methyltestosterone
1. Endocrinology and Hormonal Studies
Used to simulate androgenic effects in endocrine research, helping scientists evaluate testosterone analogues and hormonal response mechanisms.
2. Pharmaceutical Formulation Development
Employed as a reference compound in developing oral androgenic formulations, stability studies, and bioequivalence assessments.
3. Toxicology and Safety Evaluation
17?-Methyltestosterone serves as a benchmark compound in studying hepatic enzyme induction, cholestatic effects, and liver metabolism under synthetic steroid exposure.
4. Analytical and Forensic Science
Used as a reference standard in LC-MS/MS and HPLC methods for doping analysis and steroid identification in biological samples.
Commercial: Grades, Packaging, and Quality Control 17?-Methyltestosterone
1. Available Grades
| Grade | Purity | Applications |
|---|---|---|
| Analytical Grade | ? 99% | Reference standard, LC-MS calibration |
| Research Grade | ? 98% | Laboratory, pharmaceutical R&D |
| Industrial Grade | ? 95% | Bulk synthesis, chemical intermediates |
2. Packaging Options
- Available in sealed vials or aluminum foil bags from 1 g to 100 g quantities.
- Custom bulk packaging for pharmaceutical manufacturing and export.
- Supplied with COA, SDS, and purity test data for compliance.
3. Quality Testing and Standards
- Analytical Verification: HPLC, NMR, and GC/MS tested.
- Conforms to: ISO 9001 and GMP standards.
- Traceability: Batch numbers and production certificates available.
Transactional: Legal Supply and Compliance
1. Regulatory Classification
17?-Methyltestosterone is a controlled anabolic substance in many regions but may be legally obtained for research, laboratory, and pharmaceutical development purposes under proper licensing.
| Region | Regulatory Authority | Status |
|---|---|---|
| United States | DEA / FDA | Schedule III Controlled Substance – research use only with DEA registration |
| European Union | EMA / REACH | Regulated under AAS control directives; research and reference use permitted |
| United Kingdom | MHRA / Home Office | Controlled substance; available for analytical and R&D purposes |
| Asia-Pacific | Local FDA equivalents | Legal for registered labs and pharmaceutical institutions |
2. Procurement Guidelines
To ensure compliant purchase:
- Buy from certified suppliers with verifiable COA and SDS documentation.
- Verify business credentials — authorized distributors or laboratories only.
- Maintain records for compliance audits and institutional approvals.
- Ensure shipment meets customs and export control standards.
3. Safe Handling and Storage
| Hazard | Precautionary Measures |
|---|---|
| Possible irritant | Use gloves and protective eyewear |
| Avoid inhalation or ingestion | Handle in fume hood |
| Disposal | Dispose as per local chemical waste regulations |
SEO-Focused Market Overview
1. Market Demand and Research Trends
There is sustained research demand for anabolic androgenic steroids like 17?-Methyltestosterone in:
- Hormonal therapy development
- Doping control science
- Endocrine metabolism and receptor-binding assays
2. Leading Suppliers
Numerous pharmaceutical raw material companies and laboratory distributors supply 17?-Methyltestosterone for non-clinical research. Buyers should select ISO/GMP-certified sources that provide full analytical documentation.
Conclusion 17?-Methyltestosterone NEAR
17?-Methyltestosterone remains an important synthetic androgen compound for studying anabolic mechanisms, hormonal therapy development, and analytical chemistry.
For legitimate research or industrial use, buyers must ensure:
- COA-certified purity (? 98%)
- Regulatory compliance with local laws
- Procurement through authorized laboratory suppliers
By following these standards, researchers and institutions can access high-quality 17?-Methyltestosterone powder safely and legally, contributing to scientific and pharmaceutical innovation.
17?-Methyltestosterone Keywords
17?-Methyltestosterone powder • synthetic testosterone analog • anabolic androgen research • methyltestosterone reference standard • oral androgen steroid • testosterone derivative • androgen receptor assay compound • pharmaceutical raw material • GMP steroid supplier • analytical steroid research
Uses:
- Medical Applications: Treatment of low testosterone levels, delayed puberty, menopausal symptoms, and breast cancer in women.
- Administration: Taken orally or held on the cheek or under the tongue.
Side Effects:
- Masculinization: Acne, increased hair growth, voice changes, increased sexual desire.
- Estrogenic Effects: Fluid retention, breast tenderness, breast enlargement in men.
- Liver Damage: Potential risk of liver issues with prolonged use.
Chemical Properties:
- Empirical Formula: C20H30O2
- Boiling Point: Not specified
- Melting Point: Not specified
- Solubility: Not specified
Safety and Handling:
- Hazard Statements: Methyltestosterone may cause significant side effects, including masculinization and liver damage. It is important to handle the substance with care and under proper medical supervision.
Purchase Information:
- Factory Price: For wholesale inquiries and factory pricing, contact suppliers or manufacturers directly.
- Wholesale Availability: Typically available in bulk quantities. Ensure to verify the reputation and reliability of the supplier.
Legal Status:
- Controlled Substance: Methyltestosterone is a controlled substance in many countries and non-medical use is generally illicit. Ensure compliance with local regulations regarding its purchase and use.
Packaging:
- Common Packaging Options: Often available in bulk quantities. Specific packaging details will vary based on supplier and order size.
Where to Buy:
- Vendors: Purchase from reputable chemical suppliers or manufacturers who offer high-quality products and adhere to safety standards.
- Online Stores: Verify the legitimacy of online vendors and ensure they provide appropriate documentation and safety information.
Disclaimer: 17?-Methyltestosterone should be used according to prescribed medical guidelines. Non-medical use, including for physique or performance enhancement, can pose significant health risks. Always consult with a healthcare professional before use.
For purchasing, contact reliable suppliers for detailed pricing, availability, and shipping options. Ensure that you follow all legal requirements and safety guidelines when handling and using this compound.
