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Glutathione (GSH) powder is a powerful antioxidant naturally found in plants, animals, fungi, bacteria, and archaea. It plays a vital role in protecting cellular components from damage caused by reactive oxygen species, including free radicals, peroxides, lipid peroxides, and heavy metals. As a tripeptide, it consists of three amino acids—glutamate, cysteine, and glycine—linked by a gamma peptide bond between the carboxyl group of the glutamate side chain and the cysteine residue. The carboxyl group of cysteine is connected to glycine through a standard peptide bond.

Glutathione (GSH) Powder Biosynthesis and Occurrence

The biosynthesis of Glutathione (GSH) occurs in two adenosine triphosphate (ATP)-dependent steps:

  1. Gamma-glutamylcysteine formation: This step involves the enzyme glutamate–cysteine ligase (GCL), which catalyzes the combination of L-glutamate and cysteine. This is the rate-limiting step in the production of glutathione.
  2. Addition of Glycine: In the second step, glycine is added to gamma-glutamylcysteine, forming glutathione. The enzyme responsible for this reaction is glutathione synthetase.

While all animal cells can synthesize glutathione, it is particularly essential in the liver. Studies have shown that mice lacking the ability to synthesize GSH in the liver (GCLC knockout mice) die within one month of birth, highlighting the compound’s critical role. The unique gamma amide bond in glutathione protects it from degradation by peptidases.

Quick Details for Glutathione (GSH) Powder

  • Classification: Antidotes
  • CAS Number: 70-18-8
  • Chemical Name: Glutathione
  • Molecular Formula: C10H17N3O6S
  • Melting Point: 182-192°C
  • Boiling Point: 410.1°C
  • Refractive Index: 1.571
  • Flash Point: 754.5°C (at 760 mmHg)
  • Purity: 98%-101%
  • Usage: Pharmaceutical raw material
  • EINECS Number: 200-725-4
  • Synonym: Reduced Glutathione
  • Appearance: White to off-white powder
  • Shelf Life: 2 years

Packaging and Delivery

  • Packaging Options: 1 kg/foil bag; 25 kg/drum
  • Delivery Time: Within 7 days after payment is settled
  • Storage: Store in a cool, dry place; keep away from moisture

Product Specifications

Item Specification Result
Assay 98.0%-101.0% 98.5%
Appearance White to off-white powder Conforms
Specific Rotation -15.5°~-17.5° -15.8°
Loss on Drying ≤0.5% 0.40%
Residue on Ignition ≤0.1% 0.02%
Heavy Metals ≤10 ppm Conforms

High-Quality Glutathione Supplier

Glutathione (GSH) powder of high quality is available for wholesale purchase. With a purity of 98%-101%, it is suitable for various applications, including medicine, skincare, and nutritional supplements. Factories supply CAS 70-18-8 Glutathione with competitive prices and exceptional product quality.

Available Online Retailers:

  • Glutathione Powder on Lilcent Global Medical Pharmacy
  • BulkSupplements.com Glutathione Reduced Powder
  • Buy Glutathione Powder in the UK
  • Reduced Glutathione Powder (50 g)
  • Alibaba.com for Pure Glutathione Powder

Frequently Asked Questions:

  • Which form of glutathione is best absorbed?
    Reduced glutathione is considered the most bioavailable form.
  • Does glutathione come in powder form?
    Yes, glutathione is available in powder form for easy mixing into supplements or topical applications.
  • How can I make glutathione at home?
    While it is difficult to synthesize glutathione at home, there are supplements available for convenient use.
  • Can I put glutathione powder under the tongue?
    Sublingual administration of glutathione powder is possible for better absorption.

For further inquiries or to obtain a complete Certificate of Analysis (COA), feel free to contact us.

(GSH) powder is a powerful antioxidant naturally found in plants, animals, fungi, bacteria, and archaea. It plays a vital role in protecting cellular components from damage caused by reactive oxygen species, including free radicals, peroxides, lipid peroxides, and heavy metals. As a tripeptide, it consists of three amino acids—glutamate, cysteine, and glycine—linked by a gamma peptide bond between the carboxyl group of the glutamate side chain and the cysteine residue. The carboxyl group of cysteine is connected to glycine through a standard peptide bond.

Glutathione (GSH) Powder Biosynthesis and Occurrence

The biosynthesis of Glutathione (GSH) occurs in two adenosine triphosphate (ATP)-dependent steps:

  1. Gamma-glutamylcysteine formation: This step involves the enzyme glutamate–cysteine ligase (GCL), which catalyzes the combination of L-glutamate and cysteine. This is the rate-limiting step in the production of glutathione.
  2. Addition of Glycine: In the second step, glycine is added to gamma-glutamylcysteine, forming glutathione. The enzyme responsible for this reaction is glutathione synthetase.

While all animal cells can synthesize glutathione, it is particularly essential in the liver. Studies have shown that mice lacking the ability to synthesize GSH in the liver (GCLC knockout mice) die within one month of birth, highlighting the compound’s critical role. The unique gamma amide bond in glutathione protects it from degradation by peptidases.

Quick Details for Glutathione (GSH) Powder

  • Classification: Antidotes
  • CAS Number: 70-18-8
  • Chemical Name: Glutathione
  • Molecular Formula: C10H17N3O6S
  • Melting Point: 182-192°C
  • Boiling Point: 410.1°C
  • Refractive Index: 1.571
  • Flash Point: 754.5°C (at 760 mmHg)
  • Purity: 98%-101%
  • Usage: Pharmaceutical raw material
  • EINECS Number: 200-725-4
  • Synonym: Reduced Glutathione
  • Appearance: White to off-white powder
  • Shelf Life: 2 years

Packaging and Delivery

  • Packaging Options: 1 kg/foil bag; 25 kg/drum
  • Delivery Time: Within 7 days after payment is settled
  • Storage: Store in a cool, dry place; keep away from moisture

Product Specifications

Item Specification Result
Assay 98.0%-101.0% 98.5%
Appearance White to off-white powder Conforms
Specific Rotation -15.5°~-17.5° -15.8°
Loss on Drying ≤0.5% 0.40%
Residue on Ignition ≤0.1% 0.02%
Heavy Metals ≤10 ppm Conforms

High-Quality Glutathione Supplier

Glutathione (GSH) powder of high quality is available for wholesale purchase. With a purity of 98%-101%, it is suitable for various applications, including medicine, skincare, and nutritional supplements. Factories supply CAS 70-18-8 Glutathione with competitive prices and exceptional product quality.

Available Online Retailers:

  • Glutathione Powder on Amazon.com
  • BulkSupplements.com Glutathione Reduced Powder
  • Buy Glutathione Powder in the UK
  • Reduced Glutathione Powder (50 g)
  • Alibaba.com for Pure Glutathione Powder

Frequently Asked Questions:

  • Which form of glutathione is best absorbed?
    Reduced glutathione is considered the most bioavailable form.
  • Does glutathione come in powder form?
    Yes, glutathione is available in powder form for easy mixing into supplements or topical applications.
  • How can I make glutathione at home?
    While it is difficult to synthesize glutathione at home, there are supplements available for convenient use.
  • Can I put glutathione powder under the tongue?
    Sublingual administration of glutathione powder is possible for better absorption.

For further inquiries or to obtain a complete Certificate of Analysis (COA), feel free to contact us.

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