Buy Wholesale Bradykinin Powder (CAS No. 58-82-2) at Factory Prices
Acquire Bradykinin powder, identified by CAS Number 58-82-2, at wholesale factory prices. Bradykinin is a peptide with significant biological and pharmacological activities, including promoting inflammation and affecting vascular function. For detailed information or to place an order, please contact us via the website.
Product Overview
- Chemical Name: Bradykinin
- CAS Number: 58-82-2
- Molecular Formula: C50H73N15O11
- Molecular Weight: 1060.2 g/mol
- Appearance: White to off-white lyophilized solid
- Purity: ≥97% (HPLC)
- Solubility: 1 mg/mL in 5% acetic acid
- Storage Conditions: Store at −20°C in a desiccated environment; freezing is acceptable
- Color: White to off-white
- Form: Lyophilized solid
Biological Function and Applications
Bradykinin is a physiologically active peptide involved in several critical processes:
- Vascular Effects: It promotes the dilation of arterioles by inducing the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor, while constricting veins through prostaglandin F2, which leads to increased capillary leakage.
- Pain and Inflammation: Bradykinin stimulates pain receptors and contributes to inflammation and edema resulting from trauma or injury.
- Heart Recovery: It aids in post-ischemic recovery of the heart via a nitric oxide-dependent mechanism.
- Smooth Muscle Contraction: It plays a role in inducing smooth muscle contraction and vasodilation.
Pharmacological Interactions
Bradykinin levels can be increased by angiotensin-converting enzyme (ACE) inhibitors, which prevent its degradation. This enhancement of bradykinin’s effects contributes to its blood pressure-lowering impact. ACE inhibitors are FDA-approved for treating hypertension and heart failure.
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General Description
Bradykinin induces nitric oxide release and has various physiological functions, including stimulating pain receptors, inhibiting cAMP accumulation, and inducing smooth muscle contraction. It is also involved in the edema response following trauma and improves cardiac recovery post-ischemia through a nitric oxide-dependent mechanism.
Contact Information
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