Buy Wholesale Agomelatine Powder CAS No. 138112-76-2 at Factory Price

              Introduction

The global pharmaceutical market increasingly depends on high-quality active pharmaceutical ingredients (APIs) sourced from certified manufacturers. For companies engaged in psychiatric medicine, Agomelatine (CAS No. 138112-76-2) represents an innovative antidepressant API with a distinct pharmacological profile.

Buying Agomelatine in bulk at factory prices offers significant benefits to licensed buyers, including cost savings, supply chain stability, and direct access to GMP-certified sources. This guide explores what Agomelatine is, how to identify it, how wholesale sourcing works, and what steps are required to purchase responsibly.

Informational – What is Agomelatine?

                  Agomelatine is a novel antidepressant that functions differently from traditional selective serotonin reuptake inhibitors (SSRIs). It acts as a melatonergic agonist (MT1 and MT2 receptors) and a serotonin 5-HT2C antagonist, creating a dual mechanism that helps regulate circadian rhythms and improve mood.

• Primary Use: Treatment of major depressive disorder (MDD)
• Chemical Formula: C15H17NO2
• Molecular Weight: 243.3 g/mol
• CAS Number: 138112-76-2
• Appearance: White to off-white crystalline powder
• Purity Standard: ≥ 99% when manufactured under GMP conditions

Its ability to synchronize circadian rhythms makes it unique among antidepressants, offering clinical benefits in sleep regulation alongside mood stabilization.

Navigational – Identifying Agomelatine by CAS No. 138112-76-2

For buyers navigating the pharmaceutical supply chain, CAS numbers are the most reliable identifiers. The CAS No. 138112-76-2 corresponds uniquely to Agomelatine, ensuring that buyers source the correct compound without confusion.

Other identifiers include:

• INN (International Nonproprietary Name): Agomelatine
• Brand Reference: Valdoxan® (regulated markets)
• Synonyms: N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

When searching wholesale marketplaces or factory suppliers, always cross-check the CAS No. 138112-76-2 to avoid mislabeling or counterfeit products.

Commercial – Wholesale Supply & Factory Price Advantage

1. Factory Price Benefits

Purchasing directly from GMP-certified manufacturers allows buyers to obtain Agomelatine powder at factory prices, avoiding middlemen markups. This is particularly important for:

• Pharmaceutical companies formulating finished products
• Research institutions conducting clinical studies
• Distributors managing regional supply chains

2. Global Manufacturing Hubs

• China & India: Major API exporters with large-scale production
• European Union: Specialized GMP-certified production for regulated markets
• North America: Importers and licensed distributors

3. Quality Standards

Legitimate suppliers typically provide:

• Certificate of Analysis (COA)
• Good Manufacturing Practice (GMP) documentation
• Material Safety Data Sheet (MSDS)
• HPLC/GC-MS test reports confirming ≥99% purity

Factory-direct sourcing reduces cost but requires due diligence in verifying supplier credibility.

Comparison – Agomelatine vs. Other Antidepressant APIs

This comparison shows that Agomelatine offers a unique mechanism of action, differentiating it from widely used SSRIs while still meeting the same API purity and wholesale availability standards.

Transactional – How to Purchase Wholesale Agomelatine Powder

For licensed buyers, the procurement process typically follows a regulated pathway:

Step 1: Verify Supplier Credentials

• Request GMP certification
• Confirm ISO and DMF (Drug Master File) registration
• Check previous export history and client references

Step 2: Request Technical Documentation

• COA (Certificate of Analysis)
• MSDS (Material Safety Data Sheet)
• Batch testing reports

Step 3: Negotiate Factory-Direct Pricing

• Bulk orders (1kg, 5kg, 10kg+) typically qualify for significant discounts
• Compare multiple suppliers to identify the most competitive quote

Step 4: Arrange Secure Logistics

• APIs must comply with import/export regulations in the buyer’s country
• Proper temperature and stability controls during shipping
• Customs clearance documentation must be complete to avoid delays

Step 5: Ensure Legal & Regulatory Compliance

• Agomelatine is a prescription-only medicine
• Wholesale transactions are restricted to licensed pharmaceutical companies, research organizations, and approved distributors

Conclusion

Agomelatine (CAS No. 138112-76-2) is a modern antidepressant API with unique melatonergic and serotonergic properties. For pharmaceutical buyers and research institutions, sourcing Agomelatine powder wholesale at factory prices provides a strategic advantage in terms of cost efficiency, direct supplier access, and consistent product quality.

When purchasing in bulk, ensure that every transaction is backed by GMP certification, COA verification, and regulatory compliance. By following these steps, licensed buyers can integrate Agomelatine into their supply chain with confidence, while benefiting from the factory-direct price advantage.

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Agomelatine Powder for Sale

                Buy wholesale Agomelatine CAS NO. 138112-76-2 factory price . Agomelatine is an atypical antidepressant used primarily for treating major depressive disorder. It has a unique mechanism of action, functioning as a melatonergic and serotonergic agent. It was developed by Servier and is marketed under the brand names Valdoxan and Thymanax.

Uses:

• Primary Use: Treatment of major depressive disorder (MDD).
• Mechanism: Agomelatine works by blocking certain serotonin receptors and activating melatonin receptors, which may help regulate mood and sleep patterns.

Effectiveness and Side Effects:

• Effectiveness: Studies suggest it is as effective as other antidepressants, with similar rates of discontinuation due to side effects.
• Side Effects: Common side effects include weight gain, fatigue, liver issues, nausea, headaches, and anxiety. Regular blood tests are recommended due to potential liver problems. It is not recommended for individuals with dementia or those over the age of 75.

Approval and Availability:

• Approval: Agomelatine is approved in Europe and Australia but not in the United States. Approval efforts in the U.S. were discontinued in 2011.
• Form: Available as a white solid powder.

Chemical Information:

• CAS Number: 138112-76-2
• Molecular Formula: C15H17NO2
• Melting Point: 107-109°C
• Boiling Point: 478.8°C at 760 mmHg
• Refractive Index: 1.582
• Flash Point: 243.4°C
• Purity: Minimum 99%

Packaging and Delivery:

• Packaging: Typically available in foil bags, drums, or bottles.
• Delivery: Usually shipped within 3 days after payment by sea or air.

Ordering Information:

• Vendors: When buying Agomelatine powder online, ensure you are sourcing from reputable suppliers who provide high-purity products and follow safety and legal regulations.
• Price: Prices can vary depending on the supplier and order volume. Be cautious of extremely low prices as they may indicate substandard or counterfeit products.

Legal Considerations:

• Regulation: Be aware of the legal status of Agomelatine in your country. It is a prescription medication and should only be used under medical supervision.

Purchasing: To purchase Agomelatine powder, seek out established suppliers with positive reviews and proven track records in handling pharmaceutical-grade chemicals. Always verify the legitimacy of the vendor and ensure compliance with local regulations.