Buy THJ-2201 crystal online
Introduction
THJ-2201 is a synthetic cannabinoid that has drawn the attention of chemists, toxicologists, and regulatory bodies worldwide. Initially synthesized as part of pharmacological research into cannabinoid receptor agonists, it later became a compound of forensic interest after its detection in unregulated herbal blends and “legal highs.”
In legitimate research contexts, THJ-2201 serves as a reference compound for analytical laboratories studying cannabinoid receptor interactions, drug metabolism, and detection methods. This article explores its chemical characteristics, forensic relevance, and legal framework, offering a well-rounded resource for academic and industrial readers.
Informational Overview OF THJ-2201 NEAR ME
THJ-2201 belongs to the class of indazole-based synthetic cannabinoids, structurally related to AM-2201 and JWH-018 — two well-known synthetic cannabinoids studied extensively in pharmacology and toxicology.
It acts primarily as a full agonist at CB1 and CB2 receptors, producing strong cannabinoid-like effects in preclinical models. However, due to its potency and short duration, its uncontrolled use led to public-health concerns, prompting most countries to regulate it under their controlled substances legislation.
Chemical Identity and Properties
| Property | Description |
|---|---|
| IUPAC Name | 1-(5-Fluoropentyl)-1H-indazol-3-ylmethanone |
| Chemical Formula | C₂₄H₂₂FN O |
| Molecular Weight | 359.44 g/mol |
| CAS Number | 1445751-33-1 |
| Appearance | White to off-white crystalline powder |
| Melting Point | 80–85 °C (approximate) |
| Solubility | Soluble in organic solvents such as ethanol, methanol, DMSO |
| Receptor Target | CB1 and CB2 cannabinoid receptors |
| Analytical Techniques | GC-MS, LC-MS/MS, FTIR, NMR spectroscopy |
These properties make THJ-2201 an important reference material for the validation of cannabinoid detection in forensic and toxicology labs.
Navigational: Forensic and Analytical Research Applications THJ-2201
In analytical toxicology, THJ-2201 is used to develop and calibrate testing methods for synthetic cannabinoids. Its structure and spectral signatures provide valuable reference data for chromatographic and spectrometric identification of novel cannabinoids in biological and environmental samples.
Key Research Uses
- Analytical Standardization – Helps laboratories validate LC-MS and GC-MS methods for cannabinoid detection.
- Receptor Binding Studies – Enables researchers to investigate CB1/CB2 receptor affinities and pharmacokinetics.
- Metabolite Profiling – Assists in identifying THJ-2201 metabolites in biological matrices (urine, plasma).
- Forensic Casework Reference – Used as a control sample for law enforcement drug screening programs.
Because of its potency and similarity to other cannabinoids, THJ-2201 provides a benchmark compound in cannabinoid research and forensic toxicology.
Commercial: Certified Reference Materials and Laboratory Supply
While THJ-2201 cannot be sold for general or recreational use, it can be lawfully obtained through certified chemical suppliers for research, forensic, or pharmaceutical testing under strict compliance protocols.
How Laboratories Access THJ-2201 Legally
- Accredited Reference Standard Providers: Laboratories may purchase certified analytical standards of THJ-2201 from companies authorized to handle controlled substances or restricted research materials.
- Controlled Substance Licensing: In jurisdictions where THJ-2201 is regulated, research institutions must hold a controlled drugs license or DEA Schedule I registration (in the U.S.) to legally acquire and use it.
- Material Transfer Agreements (MTAs): Academic or government labs may request THJ-2201 via MTAs to ensure compliance with regulatory oversight and research ethics standards.
By working with verified suppliers and observing import/export regulations, organizations can maintain full legal compliance while conducting cannabinoid-related studies.
Transactional: Regulatory Compliance and Safe Handling THJ-2201
THJ-2201’s legal classification varies by region. Most national health and law enforcement agencies classify it under their Schedule I or Class B substance lists, meaning it is illegal to possess or distribute outside licensed research frameworks.
Legal Status Snapshot (as of 2025)
| Region | Legal Classification | Notes |
|---|---|---|
| United States | Schedule I (DEA) | Controlled under the Synthetic Drug Abuse Prevention Act |
| United Kingdom | Class B (Misuse of Drugs Act) | Prohibited synthetic cannabinoid |
| European Union | Controlled substance (varies by country) | Restricted to scientific research |
| Canada | Schedule II (Controlled Drugs and Substances Act) | Licensed use only |
| Australia | Schedule 9 (Prohibited Substance) | Research authorization required |
Safety and Storage Guidelines
- Handle THJ-2201 only in certified chemical laboratories with appropriate ventilation and protective equipment.
- Store at −20 °C in a tightly sealed container away from oxidizing agents.
- Dispose of all waste through licensed hazardous waste management channels.
- Personnel must receive chemical safety and controlled substance training before handling.
These standards ensure safe, compliant management of THJ-2201 in research environments.
Scientific and Regulatory Importance THJ-2201
Research on THJ-2201 and related cannabinoids has contributed significantly to our understanding of:
- Cannabinoid receptor signaling pathways;
- The evolution of designer drug markets;
- Toxicological profiles of synthetic cannabinoids;
- Legislative challenges in regulating emerging psychoactive substances.
By examining THJ-2201 under strict laboratory conditions, scientists can develop improved detection methods and inform public health policy regarding synthetic cannabinoid exposure.
Conclusion OF THJ-2201 crystal NEAR
THJ-2201 crystal represents a critical reference compound for forensic laboratories, analytical chemists, and regulatory researchers working to identify and control synthetic cannabinoids.
While its use is restricted under most legal frameworks, licensed laboratories can obtain THJ-2201 through authorized research channels to enhance detection accuracy and expand pharmacological understanding.
Maintaining compliance with local and international laws ensures that this compound remains a valuable scientific tool — not a public health risk. As the field of synthetic cannabinoid research evolves, the careful study of molecules like THJ-2201 will continue to guide science, safety, and regulation forward.
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Applications:
THJ-2201 is a synthetic cannabinoid commonly used in research applications. It dissolves in lipids and ethanol but remains insoluble in water, which affects its action duration when ingested. THJ-2201 is used to study cannabinoid receptors and their interactions, particularly its structural analogs.
Effects and Risks:
Physical and Cognitive Effects: Users of THJ-2201 may experience a range of effects including:
- Loss of motor control
- Enhanced tactile sensations
- Pain relief
- Altered gravity perception
- Vasodilation
- Paranoia
- Euphoria
- Increased mindfulness
- Anxiety
- Psychosis
- Slowed thoughts and decreased cognitive connectivity
Adverse Reactions: Chronic use of THJ-2201 can lead to severe side effects such as:
- Sedation
- Vertigo
- Tachycardia (rapid heartbeat)
- Possible fatalities
- Drug tolerance and dependence
Chemical Structure: THJ-2201 is an analog of AM-2201 with an indazole ring substituted with a fluoropentyl chain. The compound includes a carbonyl group bonded to a naphthalene moiety, distinguishing it as a ketone. This structure is similar to other synthetic cannabinoids like 5F-AKB-48.
Pharmacology: While not extensively studied in clinical settings, THJ-2201 is presumed to exhibit a binding profile akin to AM-2201 and Δ9-THC. It likely acts as a potent agonist for both CB1 and CB2 receptors.
Subjective Effects:
- Tactile Sensations: Often described as a warm, pleasurable tingling over the body.
- Sedation: This may cause significant relaxation and sleepiness at higher doses.
- Motor Control Loss: Can impair motor skills and coordination.
- Appetite Enhancement: Known for inducing increased appetite (“the munchies”).
- Vasodilation: This can lead to decreased blood pressure and increased heart rate.
- Pain Relief: Provides analgesic effects through cannabinoid receptor activation.
- Gravity Changes: May induce vertigo or the sensation of falling.
- Nausea: Higher doses can result in nausea and vomiting.
- Tachycardia: Potentially causes rapid heartbeat.
- Dehydration: Commonly results in dry mouth.
Precautions: THJ-2201 is a research chemical with limited clinical data. Its use can be associated with severe side effects and is linked to multiple fatalities. It is advised to use THJ-2201 only for research purposes and with appropriate safety measures.
For more information or to purchase THJ-2201, please contact certified suppliers or research chemical vendors. Ensure compliance with all applicable regulations and guidelines when handling and using this substance.









