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Overdose Risks Bromazolam has been associated with overdose cases, particularly when combined with other GABAergic substances. Despite its lower LD50 compared to some benzodiazepines, Bromazolam's LD50 is still significantly higher than typical therapeutic doses. Flumazenil, a GABA antagonist used to reverse benzodiazepine overdoses, can counteract the effects of Bromazolam as well as other traditional benzodiazepines.